Reversible Cardiomyopathy Due to Selenium Deficiency
Reeves, William, C.; Marcuard, Stefan, P.; Willis, Stephen, E.; Movahed, Assad; Reeves, William, C., East Carolina University, School of Medicine, Greenville, North Carolina; Marcuard, Stefan, P., East Carolina University, School of Medicine, Greenville, North Carolina; Willis, Stephen, E., East Carolina University, School of Medicine, Greenville, North Carolina; Movahed, Assad, East Carolina University, School of Medicine, Greenville, North Carolina
Журнал:
Journal of Parenteral and Enteral Nutrition
Дата:
1989
Аннотация:
Selenium is an essential trace element and a component of glutathione peroxidase, an enzyme that may help to prevent oxidative damage to cells. Selenium deficiency has been linked to the development of Keshan disease, a dilated congestive cardiomyopathy occurring primarily in children living in rural China.<sup>1</sup> Sporadic cases have been reported in the United States in individuals with poor nutritional intake,<sup>2-5</sup> mostly in individuals on long-term home parenteral nutrition. This report describes a young black woman with Crohn's disease in whom a congestive cardiomyopathy developed and was subsequently reversed following administration of selenium. (Journal of Parenteral and Enteral Nutrition 13:663-665, 1989)
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