Автор |
Pearson, Derek, T |
Автор |
Clayton, Richard |
Автор |
Murray, Alan |
Автор |
McArdle, Brian |
Дата выпуска |
1988 |
dc.description |
During clinical hypothermic cardiopulmonary bypass (CPB) in 20 adult patients, the ability of the perfusionist, using an alphastat acid-base blood gas management technique, to control blood gas values has been evaluated in the Bentley 10B and Bentley 10Plus bubble oxygenators. Superior flexibility in control of the blood gas values to within a defined target range (PaO<sub>2</sub> 20 ± 3.3 kPa, PaCO<sub>2</sub> 5.3 ± 0.6 kPa) with significantly improved control of PaO<sub>2</sub> was demonstrated in the Bentley 10Plus when compared with the Bentley 1 0B. The percentage of values when both PaCO<sub>2</sub> and PaO<sub>2</sub> were within the target range was higher in the Bentley 10Plus (14%) than in the Bentley 10B (11 %). The incorporation of an Integral gas proportioning valve in the Bentley 10Plus oxygenator offers a degree of independence of control of PaO<sub> 2</sub> and PaCO<sub>2</sub> which is unique in a bubble oxygenator. When the two oxygenator groups were compared, the rise in plasma haemoglobin was significantly less (p<0.005) in the Bentley 10Plus but no significant differences could be demonstrated between the two groups with respect to alteration in other formed blood elements (platelets or white blood cells) or in gaseous microemboli production. |
Издатель |
Sage Publications |
Название |
A clinical evaluation of the Bentley 10B and Bentley 10Plus bubble oxygenators |
Тип |
Other |
DOI |
10.1177/026765918800300109 |
Print ISSN |
0267-6591 |
Журнал |
Perfusion |
Том |
3 |
Первая страница |
55 |
Последняя страница |
63 |
Аффилиация |
Pearson, Derek, T, Freeman Hospital, Newcastle-upon-Tyne |
Аффилиация |
Clayton, Richard, Freeman Hospital, Newcastle-upon-Tyne |
Аффилиация |
Murray, Alan, Freeman Hospital, Newcastle-upon-Tyne |
Аффилиация |
McArdle, Brian, Freeman Hospital, Newcastle-upon-Tyne |
Выпуск |
1 |
Библиографическая ссылка |
Galletti PM, Brecher GAHeart lung bypass: principles and techniques of extracorporeal circulation . New York: Grune and Stratton , 1966. |
Библиографическая ссылка |
Swain JAAcid-base status, hypothermia and cardiac surgery. Perfusion1986; 1: 231-38. |
Библиографическая ссылка |
Govier AV, Reves JG, McKay RD et al. Factors and their influence on regional cerebral blood flow during nonpulsatile cardiopulmonary bypass. Ann Thorac Surg 1984; 38: 592-600. |
Библиографическая ссылка |
Murkin JMCBF, CMRO2 and PaCO2 during CPB. The influence of acid-base management on cerebral blood flow and metabolism during cardiopulmonary bypass . Proc Amer Acad Cardiovasc Perf 1986 ; 7: 121-23. |
Библиографическая ссылка |
Pearson DT, Holden MP, Poslad SJ, Murray A., Waterhouse PSA clinical evaluation of the gas transfer characteristics and gaseous microemboli production of two bubble oxygenators. Life Support Systems1984; 2: 252-66. |
Библиографическая ссылка |
Riley JB, Hurdle MB, Winn BA, Jallad MSUse of nitrogen in ventilation of artificial blood oxygenators. J Extracorp Tech1984; 16: 45-46. |
Библиографическая ссылка |
Kurusz M., Butler BDProblems relating to gaseous microemboli and the use of nitrogen with bubble oxygenators. J Extracorp Tech1984; 16: 114-15. |
Библиографическая ссылка |
Yost G.The bubble oxygenator as a source of gaseous microemboli. Med Instrument1985; 19: 67-69. |
Библиографическая ссылка |
Bastienen GWThe use of air with bubble oxygenators and its influence on the formation of microgas emboli. J NeSECC1984; 9: 25-27. |
Библиографическая ссылка |
Pearson DT, Poslad SJ, Murray A., Clayton R.Extracorporeal circulation material evaluation: microemboli. Life Support Systems1987; 5: 53-67. |
Библиографическая ссылка |
Severinghause JWBlood gas calculator. J Appl Physiol1966; 3: 1108-16. |
Библиографическая ссылка |
Gravelee GPCerebral blood flow during cardiopulmonary bypass. Proc Amer Acad Cardiovasc Perf1986; 7: 126-30. |
Библиографическая ссылка |
Henriksen L.Brain luxury perfusion during cardiopulmonary bypass in humans. A study of the cerebral blood flow response to changes in CO2, O2 and blood pressure. J Cerebral Blood Flow Metabolism1986; 6: 366-78. |
Библиографическая ссылка |
Pearson DT, Holden MP et al. Gaseous microemboli during open heart surgery: detection and prevention. Proc Amer Acad Cardiovasc Perf 1983; 4: 103-109. |
Библиографическая ссылка |
Butler BDBiophysical aspects of gas bubbles in blood. Med Instrument1985; 18: 59-62. |
Библиографическая ссылка |
Swain JA, White FN, Peters RMThe effect of pH on the hypothermic ventricular fibrillation threshold . J Thorac Cardiovasc Surg 1984; 87: 445-51. |
Библиографическая ссылка |
Kroncke GM, Nichols RD, Mendenhall JT, Myerowitz PD, Starling JREctothermic philosophy of acid-base balance to prevent fibrillation during hypothermia. Arch Surg1986; 121: 303-304. |
Библиографическая ссылка |
Parker D., Delpy DT, Halsall DNA new approach to inline gas monitoring: development of an oxygen sensor. Medical and Biological Engineering and Computing1983; 21: 134-37. |
Библиографическая ссылка |
Claremont DJ , Pagdin TM, Walton N. Continuous monitoring of blood PO2 in extracorporeal circuits: an in vitro analysis of a reusable oxygen electrode . Anaesthesia 1983; 39: 362-69. |
Библиографическая ссылка |
Reeder GD, Hood AGAccuracy of oxygen partial pressure measurements: an in vitro study. J Extracorp Tech1983; 15: 89-95. |
Библиографическая ссылка |
Hill AG, Vinasky RP, Todd RW, Groom RC, Lefrak EAContinuous measurement of oxygen tension during cardiopulmonary bypass . Proc Amer Acad Cardiovasc Perf 1984; 5: 39-42. |
Библиографическая ссылка |
Poslad SJ, Pearson DT, Murray A.Clinical comparison of one in vitro and three inline blood gas sensors during cardiopulmonary bypass. Clin Phys Physiol Meas1987; 8: 249-59. |
Библиографическая ссылка |
Sutherland KM, Pearson DT, Gordon LSIndependent control of blood gas parameters in a bubble oxygenator. Clin Phys Physiol Meas (in press). |
Библиографическая ссылка |
Pearson DT, Holden MP, Posald SJ, Murray A., Waterhouse PSA clinical evaluation of the performance characteristics of one membrane and five bubble oxygenators: gas transfer and gaseous microemboli production . Perfusion 1986; 1: 15-26. |