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Автор DeGandarias, Juan, M.
Автор Echevarria, Enrique
Автор Irazusta, Jon
Автор Casis, Ernesto
Автор Casis, Luis
Дата выпуска 1993
dc.description Changes in Lys-and Leu-aminopeplidase activities in several brain regions of the rat, after acute toluene administration, are described in this research. Aminopeptidase activity has been suggested as a candidate regulator of the degradation of several neuroactive peptides. Lys-aminopeptidase activity was significantly decreased in the thalamus, amygdala, and medulla oblongata. Leuaminopeptidase activity was significantly decreased in the thalamus and cerebellum. It is suggested that these aminopeptidase activities could play a part in the mechanism of toluene neurotoxicity.
Издатель SAGE Publications
Тема Leu-aminopeptidase
Тема Lys-aminopeptidase
Тема rat brain
Тема toluene
Название Lys-and Leu-Aminopeptidase Activity After Acute Toluene Exposure in the Rat Brain
Тип Journal Article
DOI 10.1177/074823379300900310
Electronic ISSN 1477-0393
Print ISSN 0748-2337
Журнал Toxicology and Industrial Health
Том 9
Первая страница 511
Последняя страница 517
Аффилиация DeGandarias, Juan, M., Department of Physiology, Medical School University of the Basque Country, Bilbao, Spain
Аффилиация Echevarria, Enrique, Department of Physiology, Medical School University of the Basque Country, Bilbao, Spain
Аффилиация Irazusta, Jon, Department of Physiology, Medical School University of the Basque Country, Bilbao, Spain
Аффилиация Casis, Ernesto, Department of Physiology, Medical School University of the Basque Country, Bilbao, Spain
Аффилиация Casis, Luis, Department of Physiology, Medical School University of the Basque Country, Bilbao, Spain
Выпуск 3
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