| Автор | Carter, Jonathan, R. |
| Автор | Lau, Manhot |
| Автор | Twiggs, Leo, B. |
| Дата выпуска | 1995 |
| dc.description | Transvaginal Doppler ultrasound was applied to 85 patients to determine whether pelvic malignancy could be predicted by pulsatility (PI) and resistive indices (RI) of intratu-moral, ovarian, and uterine vessels. Thirty-five of the patients in the study were confirmed to have malignant tumors of the cervix, uterus, or ovary. The mean intratu-moral PI and RI from malignant tumors were 0.81 (SD 0.24; range 0.3-1.2) and 0.54 (SD 0.10; range 0.27-0.62), respectively. They were significantly lower than those of the benign group (both with P < 0.05, Studentʼs t test). Thresholds of intratumoral PI < 1.0 and RI < 0.6, which differentiate malignant from benign tumors, were determined by using two receiver operating characteristic (ROC) curves. These gave a sensitivity of 94% and specificity of 63% for PI and a sensitivity of 71% and specificity of 63% for RI. The mean PI and RI from individual ovarian and uterine vessels were also significantly lower for the malignant group than those for the benign group. The authors conclude that PIs and RIs from intratumoral, ovarian, and uterine vessels are all useful in differentiating malignant tumors from benign ones, but universal thresh-olds for this purpose are far from determined. Also, comparison of intratumoral PI and RI showed that neither PI nor RI was statistically better than the other in malignancy prediction, because the areas under the two ROC curves were not statistically different (P > 0.2, chi-square method). |
| Издатель | Sage Publications |
| Название | A Comparison of Vascular Pulsatility and Resistive Indices in Gynecological Tumor Detection Using Transvaginal Ultrasound |
| Тип | Journal Article |
| DOI | 10.1177/153857449502900104 |
| Print ISSN | 1538-5744 |
| Журнал | Vascular and Endovascular Surgery |
| Том | 29 |
| Первая страница | 29 |
| Последняя страница | 35 |
| Аффилиация | Twiggs, Leo, B., Department of Obstetrics and Gynecology, University of Minnesota Medical School, Minneapolis, Minnesota |
| Выпуск | 1 |
| Библиографическая ссылка | 1. Fleicher AC, Jones HW: Early Detection of Ovarian Carcinoma with Transvaginal Sonograph-Potential and Limitations. New York: Raven Press, 1993, pp 85-144. |
| Библиографическая ссылка | 2. Folkman J: Anti-angiogenisis: New concept for therapy of solid tumors. Ann Surg 175:409-416, 1972. |
| Библиографическая ссылка | 3. Bourne T, Campbell S, Steer C, et al: Transvaginal color flow imaging: A possible new screening technique for ovarian cancer. Br Med J 299:1367-1370, 1989. |
| Библиографическая ссылка | 4. Gill RW: Accuracy calculations for ultrasound pulsed Doppler blood flow measurements. Aust Phys Eng Sci Med 5:51-57, 1982. |
| Библиографическая ссылка | 5. Hanley JA, McNeil B: The meaning and use of the area under receiver operating characteristic (ROC) curve. Radiology 143:29-36, 1982. |
| Библиографическая ссылка | 6. Kurjak A, Zalud I, Alfirevic Z, et al: The assessment of abnormal pelvic blood flow by transvaginal color and pulse Doppler. Ultrasound in Med 16:437-442, 1990. |
| Библиографическая ссылка | 7. Kurjak A, Predanic M, Kupesic S: Screening ovarian cancer by transvaginal color Doppler. In: Frontiers in Gvnecologic and Obstetric Investigation, ed. by Genazzani AR, Petraglia F, Genazzani AD. The Parthenon Publishing Group, New Jersey, 1993, pp 249-261. |
| Библиографическая ссылка | 8. Levine D, Gosink BB, Wolf SI, et al: Simple adnexal cysts: The natural history in postmenopausal women. Radiology 184:653-659, 1992. |
| Библиографическая ссылка | 9. Kawai M, Kano T, Kikkawa F, et al: Transvaginal Doppler ultrasound with color flow imaging in the diagnosis of ovarian cancer. Obstet Gynecol 79:163-167, 1992. |
| Библиографическая ссылка | 10. Thompson RS, Trudinger BJ, Cook CM: Doppler ultrasound waveform indices: A/B ratio, pulsatility index and Pourcelot ratio. Br J Obstet Gynecol 95:581-588, 1988. |
| Библиографическая ссылка | 11. Kurjak A, Zalud I: Doppler and color flow imaging. In: Transvaginal Ultrasound, ed. by Nyberg DA, Hill LM, Bohm-Velez M, et al. Mosby Year Book, St. Louis, 1992, pp 285-294. |
