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Автор Winslow, R. L.
Автор Scollan, D. F.
Автор Holmes, A.
Автор Yung, C. K.
Автор Zhang, J.
Автор Jafri, M. S.
Дата выпуска 2000
dc.description ▪ Abstract  Three topics of importance to modeling the integrative function of the heart are reviewed. The first is modeling of the ventricular myocyte. Emphasis is placed on excitation-contraction coupling and intracellular Ca<sup>2+</sup> handling, and the interpretation of experimental data regarding interval-force relationships. Second, data on use of diffusion tensor magnetic resonance (DTMR) imaging for measuring the anatomical structure of the cardiac ventricles are presented. A method for the semi-automated reconstruction of the ventricles using a combination of gradient recalled acquisition in the steady state (GRASS) and DTMR images is described. Third, we describe how these anatomically and biophysically based models of the cardiac ventricles can be implemented on parallel computers.
Формат application.pdf
Издатель Annual Reviews
Копирайт Annual Reviews
Название ELECTROPHYSIOLOGICAL MODELING OF CARDIAC VENTRICULAR FUNCTION: From Cell to Organ
DOI 10.1146/annurev.bioeng.2.1.119
Print ISSN 1523-9829
Журнал Annual Review of Biomedical Engineering
Том 2
Первая страница 119
Последняя страница 155
Аффилиация Winslow, R. L.; Whitaker Biomedical Engineering Institute, Department of Biomedical Engineering, and Center for Computational Medicine and Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205; e-mail: rwinslow@bme.jhu.edu

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