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Автор Uğurbil, Kâmil
Автор Adriany, Gregor
Автор Andersen, Peter
Автор Chen, Wei
Автор Gruetter, Rolf
Автор Hu, Xiaoping
Автор Merkle, Hellmut
Автор Kim, Dae-Shik
Автор Kim, Seong-Gi
Автор Strupp, John
Автор Zhu, Xiao Hong
Автор Ogawa, Seiji
Дата выпуска 2000
dc.description ▪ Abstract  In the short time since its introduction, magnetic resonance imaging (MRI) has rapidly evolved to become an indispensable tool for clinical diagnosis and biomedical research. Recently, this methodology has been successfully used for the acquisition of functional, physiological, and biochemical information in intact systems, particularly in the human body. The ability to map areas of altered neuronal activity in the brain, often referred to as functional magnetic resonance imaging (fMRI), is probably one of the most significant recent achievements that rely on this methodology. This development has permitted the examination of functional specialization in human and animal brains with unprecedented spatial resolution, as demonstrated by mapping at the level of orientation and ocular dominance columns in the visual cortex. These functional imaging studies are complemented by the ability to study neurochemistry using magnetic resonance spectroscopy, allowing the determination of metabolic processes that support neurotransmission and neurotransmission rates themselves.
Формат application.pdf
Издатель Annual Reviews
Копирайт Annual Reviews
Название MAGNETIC RESONANCE STUDIES OF BRAIN FUNCTION AND NEUROCHEMISTRY
DOI 10.1146/annurev.bioeng.2.1.633
Print ISSN 1523-9829
Журнал Annual Review of Biomedical Engineering
Том 2
Первая страница 633
Последняя страница 660
Аффилиация Uğurbil, Kâmil; Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis, Minnesota 55455

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