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Автор Nerem, Robert M.
Автор Seliktar, Dror
Дата выпуска 2001
dc.description ▪ Abstract  The development of a tissue-engineered blood vessel substitute has motivated much of the research in the area of cardiovascular tissue engineering over the past 20 years. Several methodologies have emerged for constructing blood vessel replacements with biological functionality. These include cell-seeded collagen gels, cell-seeded biodegradable synthetic polymer scaffolds, cell self-assembly, and acellular techniques. This review details the most recent developments, with a focus on core technologies and construct development. Specific examples are discussed to illustrate both the benefits and shortcomings of each methodology, as well as to underline common themes. Finally, a brief perspective on challenges for the future is presented.
Формат application.pdf
Издатель Annual Reviews
Копирайт Annual Reviews
Название VASCULAR TISSUE ENGINEERING
DOI 10.1146/annurev.bioeng.3.1.225
Print ISSN 1523-9829
Журнал Annual Review of Biomedical Engineering
Том 3
Первая страница 225
Последняя страница 243
Аффилиация Nerem, Robert M.; Georgia Tech/Emory Center for the Engineering of Living Tissues, Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, Georgia 30332-0363; e-mail: robert.nerem@ibb.gatech.edu seliktar@biomed.mat.ethz.ch

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