Royal Society of Chemistry по журналам "HormoneDisruptive Chemical Contaminants in Food"
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(The Royal Society of Chemistry, 2012)This chapter will provide an overview of which chemicals are contaminating our food, risks and potential adverse effects. The field of food safety research will be introduced, and we also discuss future challenges for the ...
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(The Royal Society of Chemistry, 2012)With an increasing need to screen large numbers of chemicals, computational socalled in silico methods have become of growing interest. In this chapter, in silico screening is extensively reviewed and discussed with respect ...
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(The Royal Society of Chemistry, 2012)When an item of food is found to be nontoxic by routine toxicity testing at the maximal applicable dose of 10 g kg1, the tolerable daily intake is calculated, using a safety factor of 1100, to be 100 mg kg1. Thus such a ...
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(The Royal Society of Chemistry, 2012)The general population is constantly exposed to a mixture of endocrine disrupters EDs, mainly through the food chain. This chapter reviews the multifaceted relationship between ED risk assessment and food consumption.The ...
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(The Royal Society of Chemistry, 2012)Persistent organic pollutants POPs, including organochlorine pesticides OCPs, polychlorinated dibenzodioxins and dibenzofurans PCDDFs and polychlorinated biphenyls PCBs, bioaccumulate in animal fat, which may lead to a ...
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(The Royal Society of Chemistry, 2012)Androgens produced by fetal Leydig cells FLCs during the masculinization programming window of fetal development play a critical role in the proper development of the male phenotype. An increased incidence of human male ...
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(The Royal Society of Chemistry, 2012)The susceptibility to develop noncommunicable diseases, like cardiovascular disease and cancer, depends on an interplay between the genes and the environment. Extrinsic factors, such as maternal stress hormones, dietary ...
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(The Royal Society of Chemistry, 2012)Phytoestrogens are plantderived compounds that can induce estrogenic effects in mammals. This chapter reviews the role of phytoestrogens, in particular the isoflavones from red clover and soy, as well as the prenylated ...
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(The Royal Society of Chemistry, 2012)Various compounds of either natural or synthetic origin mimic or interfere with the biological activity of hormones. Whereas some of these compounds are deactivated by their metabolism, others, such as the isoflavone ...
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(The Royal Society of Chemistry, 2012)The aryl hydrocarbon receptor AhR is a ligandactivated transcription factor that mediates the toxic effects of halogenated aromatic hydrocarbons HAHs such as polychlorinated dibenzopdioxins PCDDs, polychlorinated dibenzofurans ...
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(The Royal Society of Chemistry, 2012)Concerns about chemical contamination of the food supply and the potential risks to human populations, particularly children, emphasize the need for rapid screening methods. However, designing test systems that are both ...
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(The Royal Society of Chemistry, 2012)The current methodologies employed in the field of toxicology have a limited predicting value of toxic effects; the investigational tools are usually static in nature and detect toxicity in a snapshot of time, thus providing ...
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(The Royal Society of Chemistry, 2012)
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