| Автор | Kaffman, Arie |
| Автор | O'Shea, Erin K. |
| Дата выпуска | 1999 |
| dc.description | ▪ Abstract Information can be transferred between the nucleus and the cytoplasm by translocating macromolecules across the nuclear envelope. Communication of extracellular or intracellular changes to the nucleus frequently leads to a transcriptional response that allows cells to survive in a continuously changing environment. Eukaryotic cells have evolved ways to regulate this movement of macromolecules between the cytoplasm and the nucleus such that the transfer of information occurs only under conditions in which a transcriptional response is required. This review focuses on the ways in which cells regulate movement of proteins across the nuclear envelope and the significance of this regulation for controlling diverse biological processes. |
| Формат | application.pdf |
| Издатель | Annual Reviews |
| Копирайт | Annual Reviews |
| Название | REGULATION OF NUCLEAR LOCALIZATION: A Key to a Door |
| DOI | 10.1146/annurev.cellbio.15.1.291 |
| Print ISSN | 1081-0706 |
| Журнал | Annual Review of Cell and Developmental Biology |
| Том | 15 |
| Первая страница | 291 |
| Последняя страница | 339 |
| Аффилиация | Kaffman, Arie; Department of Biochemistry and Biophysics, University of California, San Francisco, California 94143-0448; e-mail: oshea@biochem.ucsf.edu |
