| Автор | BALL, P. |
| Автор | HARRIS, J.M. |
| Автор | LOWSON, D. |
| Автор | TILLOTSON, G. |
| Автор | WILSON, R. |
| Дата выпуска | 1995 |
| dc.description | Patients with an acute infective exacerbation of chronic bronchitis (AECB) (n = 471) were enrolled into a computer-based general-practice study to determine whether features of past history, presenting symptoms, or findings on examination were predicitive of failure to recover. The median age was 68, 56.3% were male, and 82% were current or ex-smokers. All had daily sputum production and 57.5% had moderate or severe airflow obstruction. During the AECB 11.5% were pyrexial, and 80.7% had abnormal auscultatory findings; about half had moderate to severe increases in dyspnoea and airflow obstruction, and the majority had increases in sputum volume and/or purulence. The median number of AECBs in the previous year was three, and one-third of patients had cardiopulmonarydisease. The only factors significantly (p<0.05) predicting failure to recover from an AECB were historical. Neither clinical features at presentation nor antibiotic treatment affected recovery. Coexistent cardiopulmonary disease was a risk factor for returning with a chest problem and for being referred to hospital. The number of chest infections in the previous 12 months was a risk factor for returning with a chest problem. The higher the number of chest infections, the higher the odds of returning with a chest problem. The best combination predicting return with a chest problem was history of cardiopulmonary disease and more than four previous AECBs in the last 12 months. The sensitivity was 75% and specificity 47%. |
| Формат | application.pdf |
| Издатель | Oxford University Press |
| Копирайт | © Oxford University Press |
| Тема | Original Papers |
| Название | Acute infective exacerbations of chronic bronchitis |
| Тип | research-article |
| Electronic ISSN | 1464-3855 |
| Print ISSN | 0033-5614 |
| Журнал | Quarterly Journal of Mechanics and Applied Mathematics |
| Том | 88 |
| Первая страница | 61 |
| Последняя страница | 68 |
| Аффилиация | BALL P.; Infectious Diseases Dept, Victoria Hospital |
| Аффилиация | HARRIS J.M.; Dept of Occupational and Environmental Medicine, Royal Brompton National Heart and Lung Institute |
| Аффилиация | LOWSON D.; Dept of Occupational and Environmental Medicine, Royal Brompton National Heart and Lung Institute |
| Аффилиация | TILLOTSON G.; Bayer plc, Bayer House |
| Аффилиация | WILSON R.; Host Defence Unit, Royal Brompton National Heart and Lung Institute |
| Выпуск | 1 |
