| Автор | Gray, B. M. |
| Автор | Converse, G. M. |
| Автор | Huhta, N. |
| Автор | Johnston, R. B. |
| Автор | Pichichero, M. E. |
| Автор | Schiffman, G. |
| Автор | Dillon, H. C. |
| Дата выпуска | 1981 |
| dc.description | The relationship between nasopharyngeal carriage of Streptococcus pneumoniae types 3, 19, and 23 and the development of homotypic serum antibody was examined in 17 infants followed prospectively from birth. Serially drawn sera from these children and single serumsamples from 18normal adolescents were assayed for opsonizing antibody using reduction of nitroblue tetrazolium to measure phagocytosis of killed whole pneumococci. Selected sera were also tested for quantitative antibody level by a radioimmunoassay, which correlated quite well with the nitroblue tetrazolium assay. All but one of the adolescents had antibody to type 19, and all 18 had antibody to type 23. None of the 12 infants tested for antibody to type 19 pneumococci showed evidence of an antibody response. Twoof 10infants responded to type 23 pneumococci, as did two of three infants tested to type 3 pneumococci. |
| Формат | application.pdf |
| Издатель | The University of Chicago Press |
| Копирайт | © 1981 by The University of Chicago |
| Тема | Original Articles |
| Название | Epidemiologic Studies of Streptococcus pneumoniae in Infants: Antibody Response to Nasopharyngeal Carriage of Types 3, 19, and 23 |
| Тип | research-article |
| DOI | 10.1093/infdis/144.4.312 |
| Electronic ISSN | 1537-6613 |
| Print ISSN | 0022-1899 |
| Журнал | The Journal of Infectious Diseases |
| Том | 144 |
| Первая страница | 312 |
| Последняя страница | 318 |
| Аффилиация | Gray B. M.; Department of Pediatrics, University of Alabama in Birmingham; Department of Pediatrics, National Jewish Hospital and Research Center; Department of Microbiology, State University of New York; Department of Immunology, State University of New York |
| Аффилиация | Converse G. M.; Department of Pediatrics, University of Alabama in Birmingham; Department of Pediatrics, National Jewish Hospital and Research Center; Department of Microbiology, State University of New York; Department of Immunology, State University of New York |
| Аффилиация | Huhta N.; Department of Pediatrics, University of Alabama in Birmingham; Department of Pediatrics, National Jewish Hospital and Research Center; Department of Microbiology, State University of New York; Department of Immunology, State University of New York |
| Аффилиация | Johnston R. B.; Department of Pediatrics, University of Alabama in Birmingham; Department of Pediatrics, National Jewish Hospital and Research Center; Department of Microbiology, State University of New York; Department of Immunology, State University of New York |
| Аффилиация | Pichichero M. E.; Department of Pediatrics, University of Alabama in Birmingham; Department of Pediatrics, National Jewish Hospital and Research Center; Department of Microbiology, State University of New York; Department of Immunology, State University of New York |
| Аффилиация | Schiffman G.; Department of Pediatrics, University of Alabama in Birmingham; Department of Pediatrics, National Jewish Hospital and Research Center; Department of Microbiology, State University of New York; Department of Immunology, State University of New York |
| Аффилиация | Dillon H. C.; Department of Pediatrics, University of Alabama in Birmingham; Department of Pediatrics, National Jewish Hospital and Research Center; Department of Microbiology, State University of New York; Department of Immunology, State University of New York |
| Выпуск | 4 |
