| Автор | AOYAGI, KUNIHIKO |
| Автор | OKAMURA, SEIICHI |
| Автор | SHIBUYA, TSUNEFUMI |
| Автор | MATSUGUCHI, TETSUYA |
| Автор | TSUDA, YASUO |
| Автор | YAMANO, YUJIRO |
| Автор | OTSUKA, TERUHISA |
| Автор | UEDA, AKIRA |
| Автор | NIHO, YOSHIYUKI |
| Дата выпуска | 1984 |
| dc.description | We treated a 52-year-old Japanese woman with adult T-cell leukemia (ATL) initiated with central nervous system (CNS) symptoms. Her chief complaints were paraplegia and left facial palsy. CNS-ATL was diagnosed because of the following three features. 1) Various sized lymphoid cells with marked nuclear convolution were numerous in her cerebrospinal fluid. 2) These cells were a monoclonal proliferation of T lymphocytes with OKT 4 marker. 3) The patient's serum was positive for anti-ATL associated antigen (ATLA). Although the neurological signs and symptoms improved markedly after intrathecal administration of combined chemotherapy (methotrexate, cytarabine and corti-costeroid), these ATL cells were highly resistant to radiation therapy. The abdominal mass which developed in the course of the disease was diagnosed as a tumor formed of ATL cells, and VEPA (vincristine, endoxan, prednisolone and adriamycin) was administered with marked success. |
| Формат | application.pdf |
| Издатель | Oxford University Press |
| Копирайт | © Oxford University Press |
| Тема | Adult T-cell leukemia (ATL) |
| Тема | Paraplegia |
| Тема | Facial palsy |
| Тема | CNS involvement |
| Тема | Case Reports |
| Название | A Case of Adult T-Cell Leukemia Initiated with Central Nervous System Symptoms |
| Тип | case-report |
| Electronic ISSN | 1465-3621 |
| Print ISSN | 0368-2811 |
| Журнал | Japanese Journal of Clinical Oncology |
| Том | 14 |
| Первая страница | 685 |
| Последняя страница | 690 |
| Аффилиация | The First Department of Internal Medicine, Faculty of Medicine, Kyushu UniversityFukuoka |
| Аффилиация | UEDA AKIRA; Department of Internal Medicine, Center for Adult Diseases |
| Выпуск | 4 |
