Автор |
Blerkom, Jonathan Van |
Автор |
Davis, Patrick |
Дата выпуска |
1995 |
dc.description |
This study examined the feasibility of isolating and transferring the centrosome-containing region of spermatozoa to mature human oocytes. The findings demonstrate that individual sperm centrosomes can be transferred and are capable of nucleating maternal tubulin to form a well-developed sperm aster in the recipient oocyte. The results are discussed with respect to centrosome function in early human development and applications in clinical in-vitro fertilization in the treatment of certain forms of male factor infertility. |
Формат |
application.pdf |
Издатель |
Oxford University Press |
Копирайт |
© Oxford University Press |
Тема |
microinjection |
Тема |
sperm aster |
Тема |
sperm centrosome |
Тема |
Articles |
Название |
Evolution of the sperm aster after microinjection of isolated human sperm centrosomes into meiotically mature human oocytes |
Тип |
research-article |
Electronic ISSN |
1460-2407 |
Print ISSN |
1360-9947 |
Журнал |
Molecular Human Reproduction |
Том |
1 |
Первая страница |
279 |
Последняя страница |
282 |
Аффилиация |
Department of Molecular, Cellular and Developmental Biology, University of ColoradoBoulder, CO 80309, and Reproductive Genetics In Vitro, Denver, CO 80222, USA |
Выпуск |
6 |