| Автор | Howles, C.M. |
| Автор | Macnamee, M.C. |
| Автор | Edwards, R.G. |
| Дата выпуска | 1988 |
| dc.description | Twenty-eight patients superovulated with clomiphene citrate (CC) and human menopausal gonadotrophin (HMG) were given a single injection of 25 mg progesterone (P group) 4 h prior to the ovulation-indudng injection of human chorionic gonadotrophin (HCG). Plasma and urinary LH levels were significantly higher (P < 0.05) in the P group immediately prior to HCG compared to controls. Plasma progesterone concentrations were also elevated (P < 0.01) in the P group from the time of injection to oocyte recovery. The number of mature oocytes recovered was also higher (P < 0.001; 59% versus 40% in controls) and the time interval between oocyte recovery and insemination was also shorter (P < 0.01) in the P group. The pregnancy rate/replacement 15 days after oocyte recovery was 39% versus 23% in the P and control groups respectively. It was concluded that as more mature oocytes were recovered in the P group, progesterone supplementation in the late follicular phase may be beneficial for patients undergoing GIFT. This was borne out when the first two GIFT patients pretreated in this way became pregnant. |
| Формат | application.pdf |
| Издатель | Oxford University Press |
| Копирайт | © IRL Press Limited |
| Тема | LH |
| Тема | progesterone |
| Тема | oocyte quality |
| Тема | GIFT |
| Тема | IVF |
| Тема | Reproductive endocrinology |
| Название | Progesterone supplementation in the late follicular phase of an in-vitro fertilization cycle: a ‘natural’ way to time oocyte recovery? |
| Тип | research-article |
| Electronic ISSN | 1460-2350 |
| Print ISSN | 0268-1161 |
| Журнал | Human Reproduction |
| Том | 3 |
| Первая страница | 409 |
| Последняя страница | 412 |
| Аффилиация | Bourn Hall ClinicBourn, Cambridge CB3 7TR UK |
| Аффилиация | Edwards R.G.; Physiological Laboratory |
| Выпуск | 4 |
