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Автор schiamady, Hardi
Автор Kentenich, Heribert
Дата выпуска 1989
dc.description During an in-vitro fertilization programme, 320 inseminated oocytes neither formation of pronucle nor cell cleavage were studied Cytogentically. Fourteen of 17 oocytes exhibiting no extruction of polar were characterized by an approximately diploid set of metaphase II chromosomes with four of these oocytes also showing an additional set of prematurely condensed sperm chromosomes of the G<sub>1</sub> phase (G<sub>1</sub> -PCC). These chromosomes were single chomatids. Among 211 occytes characterized by polar body extrusion, the same type of chromosomes were found in 22, along with metaphase II chromosomes in the haploid range. This phenomenon can be explained by the permanent arrest of the oocytes at metaphase II after sperm penetration, which allows the presence of the permanent arrest of the oocytes at metaphase II after sperm penetration, which allows the presence of cytoplasmic chromosome condensing factors to remain, leading to the induction of PCC in the sperm. In these cases, PCC resulted either from distinct pronuclear asnchtrony or interchromosomal asynchrony within the chromosome set.
Формат application.pdf
Издатель Oxford University Press
Копирайт © IRL Press at Oxford University Press
Тема asynchronous development
Тема inseminated human oocytes
Тема IVF
Тема premature chromosome condensation
Тема Fertilization and early embryology
Название Premature chromosome condensation after in-vitro fertilization
Тип other
Electronic ISSN 1460-2350
Print ISSN 0268-1161
Журнал Human Reproduction
Том 4
Первая страница 689
Последняя страница 695
Аффилиация Universtitätsklinikum Rudolf Vichow-Standort Charlottenburg, FrauenklinikPulsstrasse 4, D- 1000 Berlin (West) 19, FRG
Выпуск 6

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