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Автор Sacksteder, Katherine A
Автор Gould, Stephen J
Дата выпуска 2000
dc.description ▪ Abstract  The segregation of metabolic functions within discrete organelles is a hallmark of eukaryotic cells. These compartments allow for the concentration of related metabolic functions, the separation of competing metabolic functions, and the formation of unique chemical microenvironments. However, such organization is not spontaneous and requires an array of genes that are dedicated to the assembly and maintenance of these structures. In this review we focus on the genetics of peroxisome biogenesis and on how defects in this process cause human disease.
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Издатель Annual Reviews
Копирайт Annual Reviews
Название THE GENETICS OF PEROXISOME BIOGENESIS
DOI 10.1146/annurev.genet.34.1.623
Print ISSN 0066-4197
Журнал Annual Review of Genetics
Том 34
Первая страница 623
Последняя страница 652
Аффилиация Sacksteder, Katherine A; Department of Biological Chemistry, the Johns Hopkins University School of Medicine, Baltimore, Maryland

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