2,5-Disubstituted pyrrolidines: versatile regioselective and diastereoselective synthesis by enamine reduction and subsequent alkylation
Hussaini, Syed Raziullah; Moloney, Mark G.; Hussaini Syed Raziullah; The Department of Chemistry, Dyson Perrins Laboratory, The University of Oxford; Moloney Mark G.; The Department of Chemistry, Dyson Perrins Laboratory, The University of Oxford
Журнал:
Organic & Biomolecular Chemistry
Дата:
2003
Аннотация:
A direct and versatile route enabling the regio- and diastereoselective synthesis of 2,5-disubstituted pyrrolidines by reduction of enamines derived from pyroglutamic acid is reported.
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