A high current density DC magnetohydrodynamic (MHD) micropump
Homsy, Alexandra; Koster, Sander; Eijkel, Jan C. T.; van den Berg, Albert; Lucklum, F.; Verpoorte, E.; de Rooij, Nico F.; Homsy Alexandra; Institute of Microtechnology, University of Neuchâtel; KosterPresent address: Groningen Research Institute of Pharmacy, University of Groningen, The Netherlands. Sander; Institute of Microtechnology, University of Neuchâtel; Eijkel Jan C. T.; MESA + Research Institute, University of Twente; van den Berg Albert; MESA + Research Institute, University of Twente; Lucklum F.; Institute of Microtechnology, University of Neuchâtel; Verpoorte E.; Groningen Research Institute of Pharmacy, University of Groningen; de Rooij Nico F.; Institute of Microtechnology, University of Neuchâtel
Журнал:
Lab on a Chip
Дата:
2005
Аннотация:
This paper describes the working principle of a DC magnetohydrodynamic (MHD) micropump that can be operated at high DC current densities (J) in 75-µm-deep microfluidic channels without introducing gas bubbles into the pumping channel. The main design feature for current generation is a micromachined frit-like structure that connects the pumping channel to side reservoirs, where platinum electrodes are located. Current densities up to 4000 A m<sup>â 2</sup> could be obtained without noticeable Joule heating in the system. The pump performance was studied as a function of current density and magnetic field intensity, as well as buffer ionic strength and pH. Bead velocities of up to 1 mm s<sup>â 1</sup> (0.5 µL min<sup>â 1</sup>) were observed in buffered solutions using a 0.4 T NdFeB permanent magnet, at an applied current density of 4000 A m<sup>â 2</sup>. This pump is intended for transport of electrolyte solutions having a relatively high ionic strength (0.5â 1 M) in a DC magnetic field environment. The application of this pump for the study of biological samples in a miniaturized total analysis system (µTAS) with integrated NMR detection is foreseen. In the 7 T NMR environment, a minimum 16-fold increase in volumetric flow rate for a given applied current density is expected.
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