| Автор | Brivio, Monica |
| Автор | Tas, Niels R. |
| Автор | Goedbloed, Martijn H. |
| Автор | Gardeniers, Han J. G. E. |
| Автор | Verboom, Willem |
| Автор | van den Berg, Albert |
| Автор | Reinhoudt, David N. |
| Дата выпуска | 2005 |
| dc.description | The integration of a monitoring port along the microfluidic path of a MALDI-chip integrated device is described. Optimization of the microreactor design allows longer reaction and measuring times. The Schiff base reaction between 4-tert-butylaniline (1) and 4-tert-butylbenzaldehyde (2) in ethanol was carried out on-chip in the MALDI ionization chamber and the formed imine 3 was detected in real time, demonstrating the feasibility of the â monitoring windowâ approach. This preliminary result opens the way to on-chip kinetic studies by MALDI-MS, by opening multiple monitoring windows along the microchannel. |
| Формат | application.pdf |
| Издатель | Royal Society of Chemistry |
| Название | A MALDI-chip integrated system with a monitoring window |
| Тип | research-article |
| DOI | 10.1039/b418986h |
| Electronic ISSN | 1473-0189 |
| Print ISSN | 1473-0197 |
| Журнал | Lab on a Chip |
| Том | 5 |
| Первая страница | 378 |
| Последняя страница | 381 |
| Аффилиация | Brivio Monica; Laboratory of Supramolecular Chemistry and Technology, MESA<sup>+</sup> Institute for Nanotechnology, University of Twente |
| Аффилиация | Tas Niels R.; BIOS Lab-on-a-chip Group, MESA<sup>+</sup> Institute for Nanotechnology, University of Twente |
| Аффилиация | Goedbloed Martijn H.; BIOS Lab-on-a-chip Group, MESA<sup>+</sup> Institute for Nanotechnology, University of Twente |
| Аффилиация | Gardeniers Han J. G. E.; BIOS Lab-on-a-chip Group, MESA<sup>+</sup> Institute for Nanotechnology, University of Twente |
| Аффилиация | Verboom Willem; Laboratory of Supramolecular Chemistry and Technology, MESA<sup>+</sup> Institute for Nanotechnology, University of Twente |
| Аффилиация | van den Berg Albert; BIOS Lab-on-a-chip Group, MESA<sup>+</sup> Institute for Nanotechnology, University of Twente |
| Аффилиация | Reinhoudt David N.; Laboratory of Supramolecular Chemistry and Technology, MESA<sup>+</sup> Institute for Nanotechnology, University of Twente |
| Выпуск | 4 |
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