Автор |
A Morgan |
Автор |
S R Moores |
Автор |
H Morris |
Автор |
L G Nicholls |
Автор |
R J Talbot |
Дата выпуска |
1989-06-01 |
dc.description |
Groups of CBA/H mice were exposed to <sup>239</sup>PuO<sub>2</sub> by inhalation to give a range of initial alveolar deposits of 20-1660 Bq. They were killed 34 days later and free lung cells recovered by broncho-alveolar lavage. Differential cell counts were made on recovered cells and, in addition, the incidences of alveolar macrophages (AM) with aberrant nuclei and with mitotic figures were scored. The dose-response relationships for the various types of aberrant AM (micronucleate cells, binucleate cells and cells with both types of aberration) are derived. Information on the <sup>239</sup>Pu labelling index of AM is presented, and on its distribution in normal labelled AM and in labelled AM with aberrant nuclei. |
Формат |
application.pdf |
Издатель |
Institute of Physics Publishing |
Название |
Induction of nuclear aberrations in mouse alveolar macrophages following exposure to <sup>239</sup>PuO<sub>2</sub>. A dose-response study |
Тип |
paper |
DOI |
10.1088/0952-4746/9/2/006 |
Electronic ISSN |
1361-6498 |
Print ISSN |
0952-4746 |
Журнал |
Journal of Radiological Protection |
Том |
9 |
Первая страница |
129 |
Последняя страница |
135 |
Аффилиация |
A Morgan; Environ. & Med. Sci. Div., Harwell Lab., UK |
Аффилиация |
S R Moores; Environ. & Med. Sci. Div., Harwell Lab., UK |
Аффилиация |
H Morris; Environ. & Med. Sci. Div., Harwell Lab., UK |
Аффилиация |
L G Nicholls; Environ. & Med. Sci. Div., Harwell Lab., UK |
Аффилиация |
R J Talbot; Environ. & Med. Sci. Div., Harwell Lab., UK |
Выпуск |
2 |