| Автор | M. A. Micheelsen |
| Автор | C. Rischel |
| Автор | J. Ferkinghoff-Borg |
| Автор | R. Guerois |
| Автор | L. Serrano |
| Дата выпуска | 2003-02-01 |
| dc.description | We have analyzed dynamics on the complex free-energy landscape of protein folding in the FOLD-X model, by calculating for each state of the system the mean first-passage time to the folded state. The resulting kinetic map of the folding process shows that it proceeds in jumps between well-defined, local free-energy minima. Closer analysis of the different local minima allows us to reveal secondary, parallel pathways as well as dead ends. |
| Формат | application.pdf |
| Издатель | Institute of Physics Publishing |
| Копирайт | 2003 EDP Sciences |
| Название | Mean first-passage time analysis reveals rate-limiting steps, parallel pathways and dead ends in a simple model of protein folding |
| Тип | lett |
| DOI | 10.1209/epl/i2003-00165-4 |
| Electronic ISSN | 1286-4854 |
| Print ISSN | 0295-5075 |
| Журнал | EPL (Europhysics Letters) |
| Том | 61 |
| Первая страница | 561 |
| Последняя страница | 566 |
| Выпуск | 4 |
