| Автор | Rawes, JA |
| Автор | Calabrese, VP |
| Автор | Khan, OA |
| Автор | DeVries, GH |
| Дата выпуска | 1997 |
| dc.description | Antibodies to an axolemma-enriched fraction (AEF) antigen have been detected in the cerebrospinal fluid (CSF) and serum of patients with Multiple Sclerosis (MS) using an enzyme-linked immunosorbent assay (ELISA). A marginal elevation (P < 0.08) of anti-AEF lgG was found in MS CSF when compared with OND samples. When CSF was diluted to a standardized lgG concentration, the anti-AEF lgG level in MS CSF was significantly elevated (P=0.007) when compared to OND CSF. MS serum was also found to contain a significantly higher level (P < 0.00 I ) of anti-AEF lgG when compared to OND serum using the ELISA technique. |
| Издатель | Sage Publications |
| Тема | multiple sclerosis |
| Тема | axolemma-enriched fraction |
| Тема | enzyme-linked immunosorbent assay |
| Тема | immunoglobulin G |
| Тема | autoantibody |
| Тема | autoantigen |
| Название | Antibodies to the axolemma-enriched fraction in the cerebrospinal fluid and serum of patients with multiple sclerosis and other neurological diseases |
| Тип | Journal Article |
| DOI | 10.1177/135245859700300601 |
| Print ISSN | 1352-4585 |
| Журнал | Multiple Sclerosis |
| Том | 3 |
| Первая страница | 363 |
| Последняя страница | 369 |
| Аффилиация | Rawes, JA, Department of Biochemistry and Molecular Biophysics, Medical College of Virginia, Richmond, Virginia 23298-0614 USA |
| Аффилиация | Calabrese, VP, Department of Neurology, Medical College of Virginia, Richmond, Virginia 23298-0599 USA |
| Аффилиация | Khan, OA, Department of Neurology, University of Maryland, Baltimore, Maryland 21201-1595 USA |
| Аффилиация | DeVries, GH, Research Service 151, Edward Hines Jr. VA Hospital, 5th and Roosevelt Road, Hines, Illinois 60141 USA |
| Выпуск | 6 |
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