| Автор | Chorney, M.J. |
| Автор | Chorney, K. |
| Автор | Seese, N. |
| Автор | Owen, M.J. |
| Автор | Daniels, J. |
| Автор | McGuffin, P. |
| Автор | Thompson, L.A. |
| Автор | Detterman, D.K. |
| Автор | Benbow, C. |
| Автор | Lubinski, D. |
| Автор | Eley, T. |
| Автор | Plomin, R. |
| Дата выпуска | 1998 |
| dc.description | Quantitative trait loci (QTLs) associated with general cognitive ability (g) were investigated for several groups of children selected for very high or for average cognitive functioning. A DNA marker in the gene for insulin-like growth factor-2 receptor (IGF2R) on Chromosome 6 yielded a significantly greater frequency of a particular form of the gene (allele) in a high-g group (.303; average IQ = 136, N = 51) than in a control group (.156; average IQ = 103, N = 51). This association was replicated in an extremely-high-g group (all estimated IQs > 160, N = 52) as compared with an independent control group (average IQ = 101, N = 50), with allelic frequencies of .340 and .169, respectively. Moreover, a high-mathematics-ability group (N = 62) and a high-verbal-ability group (N = 51) yielded results that were in the same direction but only marginally significant (p = .06 and .08, respectively). |
| Издатель | SAGE Publications |
| Название | A Quantitative Trait Locus Associated with Cognitive Ability in Children |
| Тип | other |
| DOI | 10.1111\1467-9280.00032 |
| Electronic ISSN | 1467-9280 |
| Print ISSN | 0956-7976 |
| Журнал | Psychological Science |
| Том | 9 |
| Первая страница | 159 |
| Последняя страница | 166 |
| Аффилиация | Chorney, M.J., 1 Department of Microbiology and Immunology, Milton S. Hershey Medical Center, Pennsylvania State University |
| Аффилиация | Chorney, K., 1 Department of Microbiology and Immunology, Milton S. Hershey Medical Center, Pennsylvania State University |
| Аффилиация | Seese, N., 1 Department of Microbiology and Immunology, Milton S. Hershey Medical Center, Pennsylvania State University |
| Аффилиация | Owen, M.J., 2 Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, Wales, United Kingdom |
| Аффилиация | Daniels, J., 2 Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, Wales, United Kingdom |
| Аффилиация | McGuffin, P., 2 Department of Psychological Medicine, University of Wales College of Medicine, Cardiff, Wales, United Kingdom |
| Аффилиация | Thompson, L.A., 3 Department of Psychology, Case Western Reserve University |
| Аффилиация | Detterman, D.K., 3 Department of Psychology, Case Western Reserve University |
| Аффилиация | Benbow, C., 4 Department of Psychology, Iowa State University |
| Аффилиация | Lubinski, D., 4 Department of Psychology, Iowa State University |
| Аффилиация | Eley, T., 5 Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, United Kingdom |
| Аффилиация | Plomin, R., 5 Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, United Kingdom |
| Выпуск | 3 |
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