Автор |
Rungkat‐Zakaria, Fransiska |
Автор |
Belleville, Francine |
Автор |
Nabet, Pierre |
Автор |
Linden, Guy |
Дата выпуска |
1992 |
dc.description |
The effects of feeding cow milk casein (100 mg per day) on allergic responses in mice were studied by observing <sup>3</sup>H‐thymidine incorporation in lymphocytes and histamine release from peritoneal mastocytes. Lymphocytes cultured in the presence of casein showed proliferative activities as early as two weeks feeding up to the eighth week. This activity was not in agreement with either the positive cutaneous test or the antigenic histamine liberation. The total histamine contents in the mastocytes were found to increase from 3.2±1.9 nmol per 10<sup>5</sup> cells for the control group to 7.1 ±3.2; 6.2 ± 1.3; 6.7 ± 1.6 after four, six and eight weeks of feeding, respectively. These findings leads us to postulate that there were lymphocyte activations and mastocyte histamine accumulations as the results of intestinal permeability to casein‐derived molecules. |
Формат |
application.pdf |
Издатель |
Taylor & Francis Group |
Копирайт |
Copyright Taylor and Francis Group, LLC |
Тема |
Antigenic histamine liberation |
Тема |
casein |
Тема |
lymphocyte sensitization |
Тема |
mastocytes |
Тема |
proliferative |
Название |
Allergenicity of bovine casein. I: Specific lymphocyte proliferation and histamine accumulation in the mastocyte as a result of casein feeding in mice |
Тип |
research-article |
DOI |
10.1080/09540109209354751 |
Electronic ISSN |
1465-3443 |
Print ISSN |
0954-0105 |
Журнал |
Food and Agricultural Immunology |
Том |
4 |
Первая страница |
41 |
Последняя страница |
50 |
Аффилиация |
Rungkat‐Zakaria, Fransiska; Laboratory of Applied Biochemistry associated with INRA, University of Nancy I; Laboratory of Medical Biochemistry I, University of Nancy I; Laboratoire de Biochimie Appliquée, Université de Nancy I |
Аффилиация |
Belleville, Francine; Laboratory of Medical Biochemistry I, University of Nancy I |
Аффилиация |
Nabet, Pierre; Laboratory of Medical Biochemistry I, University of Nancy I |
Аффилиация |
Linden, Guy; Laboratory of Applied Biochemistry associated with INRA, University of Nancy I |
Выпуск |
1 |
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