| Автор | Korsrud, Gary O. |
| Автор | Macneil, James D. |
| Дата выпуска | 1988 |
| dc.description | Three bioassay procedures used for the detection of chlortetracycline (CTC) residues in tissues from swine were compared with high performance liquid chromatographic analysis. Procedures were tested on incurred tissues from 3 groups of 4 pigs each treated as follows: group B, 110 mg CTC/kg diet for 28 days; group C, 220 mg CTC/kg diet for 28 days; group D, 220 mg CTC/kg diet for 21 days, followed by 7 days without CTC in the ration. A fourth group (A) of 4 pigs were fed the same basal ration as the other 3 groups without added CTC. All tissue samples from all groups tested negative by the swab test on premises (STOP) used at slaughter plants and by a laboratory microbial inhibitor test (MIT). A thin‐layer chromatography‐bioautography (TLB) procedure currently used for STOP confirmations detected CTC residues in the liver of 1 pig from group B and 2 pigs from groups C, as well as in kidneys of 3 pigs from group B. All tissues from groups B and C, with the exception of one liver from group B, contained detectable CTC residues using HPLC analysis, as did one kidney from group D. The control tissues (group A) were free of residues. The results indicated that the TLB procedure is more sensitive for the detection of CTC residues than the STOP or the MIT procedures, and that the STOP procedure is unable to detect levels of CTC in the range of 0.1 to 1.4 μ/g in livers and kidneys from swine tested at slaughter. |
| Формат | application.pdf |
| Издатель | Taylor & Francis Group |
| Копирайт | Copyright Taylor and Francis Group, LLC |
| Тема | Chlortetracycline |
| Тема | residues |
| Тема | detection |
| Тема | swine |
| Тема | tissue |
| Название | A comparison of three bioassay techniques and high performance liquid chromatography for the detection of chlortetracycline residues in swine tissues |
| Тип | research-article |
| DOI | 10.1080/02652038809373694 |
| Print ISSN | 0265-203X |
| Журнал | Food Additives and Contaminants |
| Том | 5 |
| Первая страница | 149 |
| Последняя страница | 153 |
| Аффилиация | Korsrud, Gary O.; Animal Pathology Laboratory, Agriculture Canada |
| Аффилиация | Macneil, James D.; Animal Pathology Laboratory, Agriculture Canada |
| Выпуск | 2 |
| Библиографическая ссылка | Gale, G. O., Abbey, A. and Shor, A. 1967. Disappearance of chlortetracycline residues from edible tissues of animals fed rations containing the drug. I. Cattle and swine. Antimicrobial Agents Chemotherapy, : 749–756. |
| Библиографическая ссылка | GOVERNMENT OF CANADA. 1983. Compendium of Medicating Ingredient Brochures, |
| Библиографическая ссылка | Johnston, R. W., Reamer, R. H., Harris, E. W., Fugate, H. G. and Schwab, B. 1981. A new screening method for the detection of antibiotic residues in meat and poultry tissues. Journal of Food Protection, 44: 828–831. |
| Библиографическая ссылка | Korsrud, G. O., Naylor, J. M., Salisbury, C. D. and Macneil, J. D. 1987. A comparison of three bioassay techniques for the detection of chloramphenicol residues in animal tissues. Journal of Agricultural and Food Chemistry, 35: 556–559. |
| Библиографическая ссылка | Messersmith, R. E., Beroer, H. and Gale, G. O. 1967. Safety and tissue residue evaluations in swine fed rations containing chlortetracycline, sulfamethazine, and penicillin. Journal of the American Veterinary Medicine Association, 151: 719–724. |
| Библиографическая ссылка | Neidert, E., Saschenbrecker, P. W. and Tittiger, F. 1987. Thin layer chromatogrpahic/bioautographic method for identification of antibiotic residues in animal tissues. Journal of the Association of Official Analytical Chemists, 70(2): 197–200. |
| Библиографическая ссылка | Oka, H., Matsumoto, H., Uno, K., Harada, K., Kadowaki, S. and Suzuki, M. 1985. Improvement of chemical analysis of antibiotics. VIII. Application of prepacked C<sub>18</sub> cartridge for the analysis of tetracycline residues in animal liver. Journal of Chromatography, 325: 265–274. |
| Библиографическая ссылка | Salisbury, C. D. and Macneil, J. D. Current capabilities for monitoring antibiotic residues in animals. Abstract #36. 36th Annual Conference of Canadian Laboratory Workers in Animal Diseases. May 27. Nepean, Ontario: Animal Pathology Division,Agriculture Canada. |
| Библиографическая ссылка | Smither, R. 1978. Bacterial inhibitors formed during the adventitious growth of microorganisms in chicken liver and pig kidney. Journal of Applied Bacteriology, 45: 267–277. |
| Библиографическая ссылка | Steel, R. G. D. and Torrie, J. H. 1960. Principles and Procedures of Statistics, New York, Toronto and London: McGraw‐Hill. |
