| Автор | Marwaha, R. K. |
| Автор | Tandon, N. |
| Автор | Chopra, S. |
| Автор | Agarwal, N. |
| Автор | Garg, M. K. |
| Автор | Sharma, B. |
| Автор | Kanwar, R. S. |
| Автор | Bhadra, K. |
| Автор | Singh, S. |
| Автор | Mani, K. |
| Автор | Puri, S. |
| Дата выпуска | 2011 |
| dc.description | The present cross-sectional study was conducted to determine the vitamin D status of pregnant Indian women and their breast-fed infants. Subjects were recruited from the Department of Obstetrics, Armed Forces Clinic and Army Hospital (Research and Referral), Delhi. A total of 541 apparently healthy women with uncomplicated, single, intra-uterine gestation reporting in any trimester were consecutively recruited. Of these 541 women, 299 (first trimester, ninety-seven; second trimester, 125; third trimester, seventy-seven) were recruited in summer (April–October) and 242 (first trimester, fifty-nine, second trimester, ninety-three; third trimester, ninety) were recruited in winter (November–March) to study seasonal variations in vitamin D status. Clinical, dietary, biochemical and hormonal evaluations for the Ca–vitamin D–parathormone axis were performed. A subset of 342 mother–infant pairs was re-evaluated 6 weeks postpartum. Mean serum 25-hydroxyvitamin D (25(OH)D) of pregnant women was 23·2 (sd 12·2) nmol/l. Hypovitaminosis D (25(OH)D < 50 nmol/l) was observed in 96·3 % of the subjects. Serum 25(OH)D levels were significantly lower in winter in the second and third trimesters, while serum intact parathormone (iPTH) and alkaline phosphatase levels were significantly higher in winter in all three trimesters. A significant negative correlation was found between serum 25(OH)D and iPTH in mothers (r − 0·367, P = 0·0001) and infants (r − 0·56, P = 0·0001). A strong positive correlation was observed between 25(OH)D levels of mother–infant pairs (r 0·779, P = 0·0001). A high prevalence of hypovitaminosis D was observed in pregnancy, lactation and infancy with no significant inter-trimester differences in serum 25(OH)D levels. |
| Формат | application.pdf |
| Издатель | Cambridge University Press |
| Копирайт | Copyright © The Authors 2011 |
| Тема | Pregnancy |
| Тема | Trimesters |
| Тема | Mother–infant pairs |
| Тема | Serum 25-hydroxyvitamin D |
| Тема | Parathormone |
| Тема | Nutritional Endocrinology |
| Название | Vitamin D status in pregnant Indian women across trimesters and different seasons and its correlation with neonatal serum 25-hydroxyvitamin D levels |
| Тип | research-article |
| DOI | 10.1017/S000711451100170X |
| Electronic ISSN | 1475-2662 |
| Print ISSN | 0007-1145 |
| Журнал | British Journal of Nutrition |
| Том | 106 |
| Первая страница | 1383 |
| Последняя страница | 1389 |
| Аффилиация | Marwaha R. K.; Institute of Nuclear Medicine and Allied Sciences (INMAS) |
| Аффилиация | Tandon N.; All India Institute of Medical Sciences (AIIMS) |
| Аффилиация | Chopra S.; Armed Forces Clinic |
| Аффилиация | Agarwal N.; Institute of Home Economics, University of Delhi |
| Аффилиация | Garg M. K.; Army Hospital (Research and Referral), Delhi Cantt |
| Аффилиация | Sharma B.; Institute of Home Economics, University of Delhi |
| Аффилиация | Kanwar R. S.; Institute of Nuclear Medicine and Allied Sciences (INMAS) |
| Аффилиация | Bhadra K.; Institute of Nuclear Medicine and Allied Sciences (INMAS) |
| Аффилиация | Singh S.; Institute of Nuclear Medicine and Allied Sciences (INMAS) |
| Аффилиация | Mani K.; All India Institute of Medical Sciences (AIIMS) |
| Аффилиация | Puri S.; Institute of Home Economics, University of Delhi |
| Выпуск | 9 |
