Автор |
Bols, P.E.J. |
Автор |
de Kruif, A. |
Дата выпуска |
1995 |
dc.description |
SummaryThe experiment was set up to make a clinical comparison in 140 pneumonic calves of two injectablc oxytetracycline formulations with different pharmacokinetic properties: Engcmycin<sup>®</sup> 10% DD and Terramycin<sup>®</sup> LA. The animals were examined clinically on the day of admission (day 0) and 1,2,3, 6 and 21 days thereafter. Calves were treated on day 0 with either Engemycin<sup>®</sup> 10% DD (n=70) or Terramycin<sup>®</sup> LA (n=70) at a dose of 20 mg/kg. If animals were not cured after one single injection, a second or even third injection was given at day 3 and day 6 respectively. No significant differences between the two treatment groups were found with regard to the number of injections needed for a complete cure, the evolution of dyspnoea, or the restoration of appetite. Thus both preparations gave comparable recovery rates. A difference between the two groups existed in the evolution of body temperature during the test period: the return to a normal body temperature occured more rapidly in the Engemycin<sup>®</sup> 10% DD group. Regarding the tolerance aspects the degree of irritation depended in the preparation used. Calves treated with Engemycin<sup>®</sup> 10% DD showed significantly less swelling of the injection site on day 1 then calves treated with Terramycin<sup>®</sup> LA. |
Формат |
application.pdf |
Издатель |
Taylor & Francis Group |
Копирайт |
Copyright Taylor and Francis Group, LLC |
Название |
A clinical comparison of two injectable oxytetracycline preparations for the treatment of pneumonia in calves |
Тип |
research-article |
DOI |
10.1080/01652176.1995.9694520 |
Electronic ISSN |
1875-5941 |
Print ISSN |
0165-2176 |
Журнал |
Veterinary Quarterly |
Том |
17 |
Первая страница |
6 |
Последняя страница |
8 |
Аффилиация |
Bols, P.E.J.; Department of Obstetrics, Reproduction and Herd Health, State University |
Аффилиация |
de Kruif, A.; Department of Obstetrics, Reproduction and Herd Health, State University |
Выпуск |
1 |
Библиографическая ссылка |
Holzhouwer, C. 1992. Praktijkreeks vechouderij, 1992, Misset. 24–8. The Netherlands |
Библиографическая ссылка |
Kamminga, M, Vemooy, JCM, Schukken, YH, Pijpers, A and Verheijden, JHM. 1992. A randomized double blind clinical trial to compare the clinical recovery rate following treatment of pneumonic pigs with two longacting oxytetracycline formulations. Proceedings International Pig Veterinary Society, 12th Congress. August17–201992. pp.633 |
Библиографическая ссылка |
Nouws, JFM. 14–17 septembre 1982. “Comparative plasma oxytetracycline levels of a ‘long acting’ and a normal oxytetracycline formulation in ruminant calves”. In Congres Europeen de Pharmacologie et Toxicologie Veterinaires 14–17 septembre, 195–8. Toulouse |
Библиографическая ссылка |
Nouws, JFM, Smulders, A and Rappalini, M. 1990. A comparative study on irritation and residue aspects of five oxytetracycline formulations administered intramuscularly to calves, pigs and sheep. The Veterinary Quarterly, 12,3: 129–38. |
Библиографическая ссылка |
Prescott, JF and Baggot, DJ. 1988. “The Tetracyclines”. In Antimicrobial Therapy in Veterinary Medicine, 194–7. Oxford‐Boston: Blackwell Scientific Publications. chapter 11 |