Worldwide, honey bees are integral to agriculture because they are the most plentiful and often the most efficient pollinators of crops. Maintaining commercial populations of pollinating honey bees is vital to US agriculture. However, beekeeping is beset with many problems, including those arising from accidental importation of parasitic mites and the notorious Africanized honey bees (AHB). AHB build large populations and feral colonies, tend to invade commercial bee hives, and are highly sting-prone. Because of their tendency to sting, Africanized honey bees bring agromedical concerns. Education on avoiding stings and proactive medical planning for sting sensitive persons are appropriate responses to Africanized honey bees. Agricultural research has provided solutions to mitigate Africanization problems for beekeeping. These recommendations include management procedures that encourage the hybridization of feral populations of honey bees to help reduce stinging incidents.