Quantitative and qualitative differences in the verbal learning performance of elderly depressives and healthy controlsReprint requests to: Deborah A. King, Associate Professor of Psychiatry (Psychology), University of Rochester, Strong Memorial Hospital, 300 Crittenden Boulevard, Rochester, NY 14642-8408, USA.
King, Deborah A.; Cox, Christopher; Lyness, Jeffrey M.; Conwell, Yeates; Caine, and Eric D.; King Deborah A.; University of Rochester School of Medicine and Dentistry; Cox Christopher; University of Rochester Medical Center; Lyness Jeffrey M.; University of Rochester School of Medicine and Dentistry; Conwell Yeates; University of Rochester School of Medicine and Dentistry; Caine and Eric D.; University of Rochester School of Medicine and Dentistry
Журнал:
Journal of the International Neuropsychological Society
Дата:
1998
Аннотация:
We compared the verbal learning and memory performance of 57 inpatients with unipolar major depression and 30 nondepressed control participants using the California Verbal Learning Test. The effect of age within this elderly sample was also examined, controlling for sex, educational attainment, and estimated level of intelligence. Except for verbal retention, the depressives had deficits in most aspects of performance, including cued and uncued recall and delayed recognition memory. As well, there were interactions between depression effects and age effects on some measures such that depressivesʼ performance declined more rapidly with age than did the performance of controls. The results are discussed in the context of recent contradictory reports about the integrity of learning and memory functions in late-life depression. We conclude that there is consistent evidence, from this and other studies, that elderly depressed inpatients have significant deficits in a range of explicit verbal learning functions. (JINS, 1998, 4, 115–126.)
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