| Автор | Amass, Leslie |
| Автор | Bickel, Warren K. |
| Автор | Higgins, Stephen T. |
| Автор | Hughes, John R. |
| Дата выпуска | 1995 |
| dc.description | Eight opioid-dependent individuals were maintained on daily sublingual buprenorphine (8 mg) for 28 days and assigned randomly to one of two outpatient detoxification schedules under double-blind, double-dummy conditions. The two detoxification schedules were buprenorphine gradual (36 days; N = 3) or buprenorphine rapid (12 days; N = 5). Outcome variables were subject- and observer-ratings of opioid withdrawal, treatment retention and illicitopioid use. Outcome measures were similar for the two groups during buprenorphine maintenance. Increases in subject-rated opioid withdrawal and illicit-opioid use, and a drop in treatment retention occurred during rapid detoxification. Stable subject-rated opioid withdrawal and treatment retention, and less illicit-opioid use occurred during gradual detoxification. These data suggest that gradual reduction in buprenorphine dose is likely to produce superior treatment outcomes than more rapid buprenorphine detoxification. |
| Формат | application.pdf |
| Издатель | Taylor & Francis Group |
| Копирайт | Copyright Taylor and Francis Group, LLC |
| Название | A Preliminary Investigation of Outcome Following Gradual or Rapid Buprenorphine Detoxification |
| Тип | research-article |
| DOI | 10.1300/J069v13n03_04 |
| Electronic ISSN | 1545-0848 |
| Print ISSN | 1055-0887 |
| Журнал | Journal of Addictive Diseases |
| Том | 13 |
| Первая страница | 33 |
| Последняя страница | 45 |
| Аффилиация | Amass, Leslie; Department of Psychiatry, University of Vermont, Burlington, VT, 05401 |
| Аффилиация | Bickel, Warren K.; Departments of Psychiatry and Psychology, University of Vermont, Burlington, VT 05401 |
| Аффилиация | Higgins, Stephen T.; Departments of Psychiatry and Psychology, University of Vermont, Burlington, VT 05401 |
| Аффилиация | Hughes, John R.; Departments of Psychiatry, Psychology and Family Practice, University of Vermont, Burlington, VT 05401 |
| Выпуск | 3 |
