| Автор | Kosower, E. M. |
| Автор | Waits, Harold P. |
| Дата выпуска | 1971 |
| Формат | application.pdf |
| Издатель | Taylor & Francis Group |
| Копирайт | Copyright Taylor and Francis Group, LLC |
| Название | 1-ETHYL-4-CARBOMETHOXYPYRIDINYL (Pyridinyl, 1-ethyl-4-carbomethoxy) |
| Тип | research-article |
| DOI | 10.1080/00304947109356786 |
| Electronic ISSN | 1945-5453 |
| Print ISSN | 0030-4948 |
| Журнал | Organic Preparations and Procedures International |
| Том | 3 |
| Первая страница | 261 |
| Последняя страница | 267 |
| Аффилиация | Kosower, E. M.; Department of Chemistry, State University of New York |
| Аффилиация | Waits, Harold P.; Department of Chemistry, State University of New York |
| Выпуск | 5 |
| Библиографическая ссылка | Kosower, E. M. and Poziomek, E. J. 1964. J. Am. Chem. Soc., 86: 5515 |
| Библиографическая ссылка | Schwarz, W. M., Kosower, E. M. and Shain, I. 1961. J. Am. Chem. Soc., 83: 3164 |
| Библиографическая ссылка | Kosower, E. M. and Schwager, I. 1964. J. Am. Chem. Soc., 86: 5528 E. M. Kosower and Y. Ikegami, ibid., 89, 461(1967); ibid., 90, 1943(1968); E. M. Kosower and M. Mohammad, ibid., 90, 327(1968); M. Mohammad and E. M. Kosower, ibid., 93, 2709(1971). |
| Библиографическая ссылка | Methyl isonicotinate (Reilly Tar & Chemical Corp., Indianapolis, Indiana) and ethyl iodide in ethanol or acetone at reflux for 5–8 hours yield the required quaternary salt. Recrystallization from acetone producesorange crystals, m.p. 110–112°. The color of the salt is due to light absorption in the charge-transfer band, not impurities. |
| Библиографическая ссылка | Fieser, L. F. 1967. Reagents for Organic Synthesis, 1030John Wiley and Sons, Inc.. Sodium amalgam is prepared according to the directions given in |
| Библиографическая ссылка | The vacuum line equipped with a mercury diffusion pump, a forepump and traps is operated at a pressure of 1 × 10 mm. Long pumping times ensure removal of adsorbed oxygen. |
| Библиографическая ссылка | Acetonitrile (Spectroquality) from Matheson Coleman and Bell or J. T. Baker, is satisfactory for this preparation. |
| Библиографическая ссылка | The relatively high (-40° C.) melting point of acetonitrile can lead to difficulty (even cracking of apparatus) if care is not exercised in the melting operation. A beaker of acetone at room temperature is ideal for this step. |
| Библиографическая ссылка | Data are: λ<sub>max</sub> (λ<sub>max</sub>) 6325(83), 3940(4925), 3100(11,000). The visible maximum does not obey Beer's Lav above ∼ 0.03 M due to reversible dimerization. |
| Библиографическая ссылка | Acetonitrile solutions of 1-ethyl-4-carbomethoxypyridinyl (∼0.01 - .02 M) have been stored for many months with little apparent decomposition. |
