| Автор | Moradi, Masoumeh |
| Автор | Hassan Eftekhari, Mohammad |
| Автор | Talei, Abdolrasoul |
| Автор | Rajaei Fard, Abdolreza |
| dc.description | AbstractObjectiveThe present study was undertaken to compare plasma Se values and glutathione peroxidase (GPX) activity in normal and breast cancer patients.DesignIn a case–control study, forty-five breast cancer patients and the same number of healthy women were randomly selected from their population. Se was measured in plasma by atomic absorption spectrophotometry and GPX activity in erythrocytes was measured using a standard spectrophotometric method.ResultsPlasma Se concentration in healthy women and breast cancer patients was in the normal range, with no statistically significant difference observed between the two groups (138·40 (sd 40·36) μg/l v. 132·15 (sd 35·37) μg/l, respectively). Erythrocyte GPX activity was significantly (P<0·01) higher in breast cancer patients (24·81 (sd 11·66) U/g Hb) compared with healthy women (20·29 (sd 4·24) U/g Hb).ConclusionThe present study indicated that Se deficiency was not a problem in the participants, and sufficient quantity of this element could increase GPX activity to have a protective effect against oxidative damage. |
| Формат | application.pdf |
| Издатель | Cambridge University Press |
| Копирайт | Copyright © The Authors 2008 |
| Тема | Antioxidant |
| Тема | Breast cancer |
| Тема | Glutathione peroxidase |
| Тема | Selenium |
| Название | A comparative study of selenium concentration and glutathione peroxidase activity in normal and breast cancer patients |
| Тип | research-article |
| DOI | 10.1017/S1368980008001924 |
| Electronic ISSN | 1475-2727 |
| Print ISSN | 1368-9800 |
| Журнал | Public Health Nutrition |
| Том | 12 |
| Первая страница | 59 |
| Последняя страница | 63 |
| Аффилиация | Moradi Masoumeh; Shiraz University of Medical Sciences |
| Аффилиация | Hassan Eftekhari Mohammad; Shiraz University of Medical Sciences |
| Аффилиация | Talei Abdolrasoul; Shiraz University of Medical Sciences |
| Аффилиация | Rajaei Fard Abdolreza; Shiraz University of Medical Sciences |
| Выпуск | 1 |
