| Автор | Riley, E. M. |
| Автор | Chappell, L. H. |
| Дата выпуска | 1990 |
| dc.description | Praziquantel, administered over a 72 h period in the food of mature Biomphalaria glabrata harbouring 7-week-old Schistosoma mansoni infections, dramatically reduced the numbers of cercariae shed. Doses of 20–30 μg/g body weight (including shell weight) reduced shedding by 85–95% over 5 weeks before recovery was evident. Suppression of cercarial shedding in these infections was accompanied by the temporary recovery of the snail reproductive regression due to S. mansoni infection. Snail fecundity was subsequently re-suppressed 2 weeks prior to recovery of the parasite as evidenced by a resumption of cercarial shedding. Praziquantel destroyed mature and developing cercariae within the daughter sporocysts but had no apparent effect on daughter sporocysts; this may account for the eventual resumption of cercarial production. Reproductive failure of the snail is apparently related to the latter stages of cercarial development specifically. Reproductive recovery did not occur when snails were infected as juveniles or when mature-infected snails harboured 12–5 week i.e. older infections: drug treatment temporarily inhibited cercarial production but no snails produced eggs. |
| Формат | application.pdf |
| Издатель | Cambridge University Press |
| Копирайт | Copyright © Cambridge University Press 1990 |
| Тема | Schistosoma mansoni |
| Тема | Biomphalaria glabrata |
| Тема | praziquantel |
| Тема | fecundity |
| Название | Praziquantel treatment of Biomphalaria glabrata infected with Schistosoma mansoni– influence on snail fecundity |
| Тип | research-article |
| DOI | 10.1017/S0031182000063253 |
| Electronic ISSN | 1469-8161 |
| Print ISSN | 0031-1820 |
| Журнал | Parasitology |
| Том | 101 |
| Первая страница | 211 |
| Последняя страница | 217 |
| Аффилиация | Riley E. M.; University of Aberdeen |
| Аффилиация | Chappell L. H.; University of Aberdeen |
| Выпуск | 2 |
