Автор |
Jansen, E. H. J. M. |
Автор |
van den Berg, R. H. |
Автор |
Van Blitterswijk, H. |
Автор |
Both‐Miedema, R. |
Автор |
Stephany, R. W. |
Дата выпуска |
1985 |
dc.description |
A specific radioimmunoassay (RIA) for diethylstilbestrol (DES) is presented following purification of sample extracts by isocratic reversed phase high performance liquid chromatography. Applications are given of a forensic investigation for the control of DES in bovine urine. Specificity of HPLC‐RIA is compared with that of RIA's with other (Chromatographic) purification procedures and with gas chromatography‐mass spectrometry. Implications of the use of these techniques in practice and the use of various DES‐antisera are discussed. |
Формат |
application.pdf |
Издатель |
Taylor & Francis Group |
Копирайт |
Copyright Taylor and Francis Group, LLC |
Название |
A highly specific detection method for diethylstilbestrol in bovine urine by radioimmunoassay following high performance liquid chromatography |
Тип |
research-article |
DOI |
10.1080/02652038509373556 |
Print ISSN |
0265-203X |
Журнал |
Food Additives and Contaminants |
Том |
2 |
Первая страница |
271 |
Последняя страница |
281 |
Аффилиация |
Jansen, E. H. J. M.; Laboratory for Endocrinology, National Institute of Public Health and Environmental Hygiene |
Аффилиация |
van den Berg, R. H.; Laboratory for Endocrinology, National Institute of Public Health and Environmental Hygiene |
Аффилиация |
Van Blitterswijk, H.; Laboratory for Endocrinology, National Institute of Public Health and Environmental Hygiene |
Аффилиация |
Both‐Miedema, R.; Laboratory for Endocrinology, National Institute of Public Health and Environmental Hygiene |
Аффилиация |
Stephany, R. W.; Laboratory for Endocrinology, National Institute of Public Health and Environmental Hygiene |
Выпуск |
4 |
Библиографическая ссылка |
Abraham, G. E. 1969. Solid phase radioimmunoassay of estradiol‐17ß. Journal of Clinical Endocrinology and Metabolism, 29: 866–870. |
Библиографическая ссылка |
Benraad, Th., J., Stephany, R. W., Rosmalen, F. M. A., Hofman, J. A., Loeber, J. G. and Elvers, L. H. 1981. The necessity of Chromatographie purification prior to radioimmunoassay of diethylstilbestrol in the urine of cattle. Veterinary Quarterly, 3: 153–157. |
Библиографическая ссылка |
Bundesgesundheitsamt, Federal German Republic. 1983. Nachweismethoden für Rückstände im Rahmen der amtlichen Schlachttier‐ und Fleischuntersuchung. Stilbenderivate Diäthylstilböstrol, Hexöstrol und Dienöstrol in Urin, Galle, Fäzes und Geweben von Mastkälbern und Bullen (RIA). Bundesgesundheitsblatt, 26: 17–21. |
Библиографическая ссылка |
Derks, H. J. G. M., Freudenthal, J., Litjens, L. J. M., Klaassen, R., Gramberg, L. G. and Borrias‐van Tongeren, V. 1983. Identification and quantification of diethylstilbestrol in the urine of cattle by both low and high resolution gaschromatography mass spectrometry. Biomedical Mass Spectrometry, 10: 209–214. |
Библиографическая ссылка |
Jansen, E. H. J. M. and Stephany, R. W. 1985. Effective control for diethylstilbestrol in cattle in The Netherlands. Veterinary Quarterly, 7: 35–38. |
Библиографическая ссылка |
Jansen, E. H. J. M., Van den Berg, R. H., Van Blitterswijk, H., Both‐Miedema, R. and Stephany, R. W. 1984. Identification of several stilbene derivatives in bovine urine by means of high performance liquid Chromatographie fractionation and immunochemical detection. Veterinary Quarterly, 6: 5–7. |
Библиографическая ссылка |
Jansen, E. H. J. M., Both‐Miedema, R., Van Blitterswijk, H. and Stephany, R. W. 1984. Separation and purification of several anabolics in bovine urines by high performance liquid chromatography. Journal of Chromatography, 299: 450–455. |
Библиографическая ссылка |
Laboratoire d'hormonologie, 5406 Marloie, Belgium. Data sheet for antibody Anti‐DES, lot no D 105. |
Библиографическая ссылка |
Liemann, F., Muschke, M., 1981. Ein Radioimmunoassay zum direkten Nachweis von Diäthylstilböstrol‐Glucuronid und östrogen wirksamen Stilbenen zur routinemässigen Rückstands‐überwachung. Archiv für Lebensmittelhygiene. 32 110–115 |
Библиографическая ссылка |
Ministry of Welfare, Health and Cultural Affairs, The Netherlands. 1983. “Meat Inspection Act. Modification of the Investigation Regulation and Inspection Regulation”. In Nederlandse Staatscourant Vol. 250, 10–13. (in Dutch). English translation of the detailed RIA parts is available as: |
Библиографическая ссылка |
Stephany, R. W., Loeber, J. G., Jansen, E. H. J. M. and Schmidt, N. A. 1984. CEC documents VI/2447/84‐EN and VI/2448/84‐EN, Brussels, , Belgium: Commission of the European Communities. VI/B/4 |
Библиографическая ссылка |
Rodbard, D. and Lewald, J. E. 1970. Computer analysis of radioligandassay and radioimmunoassay data. Acta Endocrinologia, : 79–103. |
Библиографическая ссылка |
Roussel‐Uclaf, Centre de Recherches, 932330 Romainville, France. Data sheet for antibody Anti‐DES, batch no 254. |
Библиографическая ссылка |
Stephany, R. W. 1982. “The detection of diethylstilbestrol (DES) in the urine of veal calves and cattle via various chemical methods. A cooperative study in The Netherlands during 1981”. In First Report of the national working group ‘Evaluation of methods of analysis and distribution of hormone research activities (EVATH)’ (in Dutch), Bilthoven, , The Netherlands: National Institute of Public Health. |