Strawberry anthocyanin and its association with postprandial inflammation and insulin
Edirisinghe, Indika; Banaszewski, Katarzyna; Cappozzo, Jack; Sandhya, Krishnankutty; Ellis, Collin L.; Tadapaneni, Ravi; Kappagoda, Chulani T.; Burton-Freeman, Britt M.; Edirisinghe Indika; National Center for Food Safety and Technology, Illinois Institute of Technology; Banaszewski Katarzyna; National Center for Food Safety and Technology, Illinois Institute of Technology; Cappozzo Jack; National Center for Food Safety and Technology, Illinois Institute of Technology; Sandhya Krishnankutty; National Center for Food Safety and Technology, Illinois Institute of Technology; Ellis Collin L.; University of California-Davis; University of California-Davis; Tadapaneni Ravi; National Center for Food Safety and Technology, Illinois Institute of Technology; Kappagoda Chulani T.; University of California-Davis; Burton-Freeman Britt M.; National Center for Food Safety and Technology, Illinois Institute of Technology; University of California-Davis
Журнал:
British Journal of Nutrition
Дата:
2011
Аннотация:
The present study investigates the effect of strawberry antioxidants in beverage form on meal-induced postprandial inflammatory and insulin responses in human subjects. Overweight adults (n 24) consumed a high-carbohydrate, moderate-fat meal (HCFM) accompanied by either a strawberry or a placebo beverage in a cross-over design. Postprandial changes in plasma anthocyanins, their metabolites, insulin, glucose and inflammatory markers were assessed for 6 h. The postprandial concentrations of pelargonidin sulfate and pelargonidin-3-O-glucoside were significantly increased when the strawberry beverage was consumed concurrently with the HCFM compared with the placebo beverage (P < 0·001). The strawberry beverage significantly attenuated the postprandial inflammatory response as measured by high-sensitivity C-reactive protein and IL-6 (P < 0·05) induced by the HCFM. It was also associated with a reduction in postprandial insulin response (P < 0·05). Collectively, these data provide evidence for favourable effects of strawberry antioxidants on postprandial inflammation and insulin sensitivity.
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